Born in Tokyo. Keiko lived in the United States from age four to six. She went to and graduated from Shirayuri Gakuen Middle and High School. After graduating Tokyo University, she made her debut as in-home tutor, Keiko-sensei, on the TV program Susunu! Denpa Shōnen. She appeared on TV, in programs including: Emergency Room 24 Hours, Star's Love, Waratte Iitomo!, Tokyo Friend Park, and commercials for Shiseido, House, etc.. Keiko also appeared in magazines including: Tarzan, Croissant, and Pia of which she was on the cover.
In 2003, Keiko became an apprentice to the master of female Rōkyoku of Kamigata, the holder of Osaka's Important Intangible Cultural Property, The Second Yuriko Haruno. She buzzed her hair off and started training. She performed regularly in events including: Isshinjimonzenyose, Kamigata Rakugo Joseki Tenmatenjinhanjōtei, Yamamoto Nōgaku-dō's Kamigata Dentō Geinō Night, Kokuritsu Bunraku Gekijō's Kamigata Engei Tokusen-kai. She also performed in NHK's Kamigata Engei Hall, Warai ga Ichiban, Seikatsu Shō-hyakka, Ruson no Tsubo, Touzai Rōkyoku Tokusen, Mainichi Hōsō's Chichin Puipui, Yomiuri Television's Takajin no Sokomade Itte Iinkai, and Asahi Television's Kuizu Purezen Baraetii Q-sama.
Keiko has also been mentioned in the media for conducting a Rōkyoku concert tour which included her Rōkyoku workshop, Keiko Haruno's Rōkyoku Rock You! Other concert tours include: Kyōyama Kōshiwaka ga Haruno Keiko wo Shigoku Kai, Keiko Haruno's Musha-shugyō Jūgoban-shōbu, Keiko & Hazuki's Tokyo Rōkyoku Jungyō no Tabi, and Keiko Haruno's Cafe de Rōkyoku.
In 2009, she played the heroine in the movie, Anata no Tamenara Doko Mademo, directed by Ayame Katsura. She also appeared in many theatrical acts. She played the main character, Michiko Kambayashi, in Hiryūden, produced by The Isshinji Theater Club as a tribute to Tsuka Kōhei in 2011. From the fall of 2013 to 2014, Keiko will guest star in Mangetsu, performed by the popular theatrical company Minamikawachi Banzai Ichiza.
In 2012, she performed in Rōkyoku Chūshingura at Kokuritsu Bungaku Gekijō. She received the Sakuya Kono Hana Award in the popular entertainment category.
In March 2013, Keiko performed a full-scale Rōkyoku in English for the first time in history. She sang the national anthem before the Orix vs Hanshin baseball game at the Kyocera Stadium. She wrote for the column Hidamari Cafe in the Yomiuri Shinbun newspaper and started working as the director of The Public Interest Incorporated Association, Rōkyoku Shinyūkai.
Keiko organized her Rōkyoku 10 year anniversary event, Haruno Keiko Rōkyoku-kai, which will take place on Sunday, November 10th of this year at Yamamoto Nōgaku-Dō. She plans to perform new Rōkyoku titles, which take place in modern time, produced by the Rakugo writer, Akane Kumazawa, as a part of the National Arts Festival of Heisei 25 (2013) hosted by The Agency for Cultural Affairs.